Lanying Du
Faculty Distinguished University Professor- Biography
Dr. Du is a Distinguished University Professor in the Institute for Biomedical Sciences at Georgia State University. Her research mainly focuses on the rational design and development of effective and safe medical countermeasures to prevent and treat viral diseases and cancer.
Dr. Du is listed among the Highly Cited Researchers from 2021 to 2024 by the Web of Science (Clarivate). Dr. Du is also listed among the world’s top 2 percent most-cited scientists from 2021 to 2024 by Stanford University.
Research Interests
- Research and development of medical countermeasures to prevent and treat infection caused by flaviviruses, including Zika virus, Dengue virus, and other flaviviruses with epidemic or pandemic potential.
- Research and development of medical countermeasures to prevent and treat infection caused by pathogenic coronaviruses with epidemic or pandemic potential.
- Research and development of medical countermeasures to prevent and treat diseases caused by other viruses or pathogens, as well as exploration of effective approaches for cancer therapies.
- Research fields and tools: virology, immunology, cell biology, molecular biology, structural biology, and other related fields, nanotechnologies, vaccine design, characterization, and evaluation, antibody generation and evaluation, drug screening and validation, etc.
- Publications
- Yang Y, Li F, Du L. Therapeutic nanobodies against SARS-CoV-2 and other pathogenic human coronaviruses. J Nanobiotechnology. 2024;22(1):304.
- Wang G, Verma AK, Shi J, Guan X, Meyerholz DK, Bu F, Wen W, Liu B, Li F, Perlman S, Du L. Universal subunit vaccine protects against multiple SARS-CoV-2 variants and SARS-CoV. NPJ Vaccines. 2024;9(1):133.
- Shi J, Zheng J, Zhang X, Tai W, Compas R, Deno J, Jachym N, Verma AK, Wang G, Guan X, Odle AE, Wan Y, Li F, Perlman S, Qiao L, Du L. A T cell-based SARS-CoV-2 spike protein vaccine provides protection without antibodies. JCI Insight. 2024;9(5):e155789.
- Wang G, Verma AK, Guan X, Bu F, Odle AE, Li F, Liu B, Perlman S, Du L. Pan-beta-coronavirus subunit vaccine prevents SARS-CoV-2 Omicron, SARS-CoV, and MERS-CoV challenge. J Virol. 2024;98(9):e0037624.
- Roy A, Liu Q, Yang Y, Debnath AK, Du L. Envelope protein-targeting Zika virus entry inhibitors. Int J Mol Sci. 2024;25(17):9424.
- Guan X, Yang Y, Du L. Advances in SARS-CoV-2 receptor-binding domain-based COVID-19 vaccines. Expert Rev Vaccines. 2023;22(1):422-439.
- Shi J, Wang G, Zheng J, Verma AK, Guan X, Malisheni MM, Geng Q, Li F, Perlman S, Du L. Effective vaccination strategy using SARS-CoV-2 spike cocktail against Omicron and other variants of concern. NPJ Vaccines. 2022;7(1):169.
- Yang Y, Du L. Neutralizing antibodies and their cocktails against SARS-CoV-2 Omicron and other circulating variants. Cell Mol Immunol. 2022;19(8):962-964.
- Du L, Yang Y, Zhang X, Li F. Recent advances in nanotechnology-based COVID-19 vaccines and therapeutic antibodies. Nanoscale. 2022;14(4):1054-1074.
- Tai W, Zhang X, Yang Y, Zhu J, Du L. Advances in mRNA and other vaccines against MERS-CoV. Transl Res. 2022;242:20-37.